NCT04611984

OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment

Osteocalcin and Cross-Linked C-Terminal Telopeptides of Type I Collagen in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Tooth Movement

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Marmara University · Academic / Other
• Sex: All
• Age: 13 Years – 20 Years
• Healthy volunteers: Accepted

Summary

The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.

Detailed description

15 systemically healthy subjects requiring extraction of the maxillary 1. premolars with distalization of the maxillary canines were enrolled to the study. Piezocisions were performed on the distal and mesial sides of the right maxillary canines while the left maxillary canines served as controls. Canine distalization was performed via closed-coil springs applying 150 g of force per side by using miniscrews as anchorage. Gingival crevicular fluid samples were collected from both mesial and distal sides of right and left maxillary canines at 0, 1, 7, 14 and 28 days. The gingival crevicular fluid levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen were determined by using ELISA. The rate of tooth movement was measured on 14 and 28 days.

Conditions

• Tooth Movement

Interventions

Type	Name	Description
PROCEDURE	Piezocision	Piezocisions were performed on the mesial and distal sides of the right maxillary canines. Then canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage.
PROCEDURE	Control	The mesial and distal sides of the left maxillary canines served as controls and canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage.

Timeline

• Start date: 2013-03-01
• Primary completion: 2014-08-01
• Completion: 2014-08-01
• First posted: 2020-11-02
• Last updated: 2020-11-02

Locations

1 site across 1 country: Turkey (Türkiye)