NCT04611945

Westlake Sailing Cohort

Westlake Sailing Cohort: Dynamic Change of Human Microbiome During Sailing

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 17 (actual)
• Sponsor: Westlake University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Little is known about the dynamic change of human microbiome in different body sites including skin, mouth and gut during sailing. The present study aims to reveal the change of human microbiome in response to the sailing environment in a 1-month period, and its implication for human health.

Detailed description

This study will recruit a number of participants who are going to sail for mariana trench from Shenzhen, China. Characteristics of the participants will be described by a series of index of stool, urine, skin microbiota and tongue coating. All the biospecimen will be collected before and during the voyage. Stool at the 2nd, the 4th and the 12th week after the voyage and blood sample at the baseline will also be collected. Participants' mood states, health-related quality of life, fatigue score and sleep quality will be investigated with questionnaires throughout the 1-month period. Participants are asked to record diseases and symptoms, if any, when sailing. All the data will be used to analyse how microbiota change and be involved in human health during a voyage.

Conditions

• Microbiome
• Glucose Metabolism
• Mood
• Environment

Timeline

• Start date: 2020-11-10
• Primary completion: 2022-01-31
• Completion: 2022-04-26
• First posted: 2020-11-02
• Last updated: 2022-04-28

Locations

1 site across 1 country: China