NCT04610203

Glycaemic Response, Insulinaemic Response, GLP-1 and GIP Testing of Food Product Lines

Glycaemic, Insulinaemic, Gastric Inhibitory Polypeptide (GIP) and Glucagon-like Peptide-1 (GLP-1) Response for Glucose, Glucose With 25 g Nutralys S85 Plus and Glucose With 50 g Nutralys S85 Plus

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Oxford Brookes University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The aim of this study was to compare the glycaemic response, insulinaemic response, GIP response and GLP-1 response to glucose, 25 g Nutralys S85 Plus and 50 g Nutralys S85 Plus using a single-blind, randomised, repeat measure, crossover design trial.

Detailed description

The aims of this study were to examine: * Phase I - the glycaemic response (GR) and insulinaemic response (IR) to: * 50 g available carbohydrate * 50 g available carbohydrate + protein (dose 1) * 50 g available carbohydrate + protein (dose 2) * Phase II - the GLP-1 and GIP response to: * 50 g available carbohydrate * 50 g available carbohydrate + protein (dose 1) * 50 g available carbohydrate + protein (dose 2) A single-blind, randomised, repeat measure, crossover design trial was used to study the response following consumption of three meals: one reference meal (50 g available carbohydrate) and two test meals (50 g available carbohydrate with protein dose 1 and 50 g available carbohydrate with protein dose 2). The study was conducted in two phases: * Phase I: glycaemic response (GR), insulinaemic response (IR) * Phase II: GLP-1 response and GIP response

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	25 g Nutralys Pea Protein	To determine the glycaemic response, insulinaemic response, GIP response and GLP-1 response to 50g Glucose +25g Nutralys S85 Plus
DIETARY_SUPPLEMENT	50 g Nutralys S85 Plus.	To determine the glycaemic response, insulinaemic response, GIP response and GLP-1 response to 50g Glucose+50 g Nutralys S85 Plus .
DIETARY_SUPPLEMENT	50 g Glucose	To determine the glycaemic response, insulinaemic response, GIP response and GLP-1 response to 50g Glucose

Timeline

• Start date: 2018-12-03
• Primary completion: 2019-07-05
• Completion: 2019-09-30
• First posted: 2020-10-30
• Last updated: 2020-11-02

Locations

1 site across 1 country: United Kingdom