Trials / Completed
CompletedNCT04608123
Effect of Deep Brain Stimulation on Neuropsychiatric Fluctuations in Patients With Parkinson's Disease
Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Neuropsychiatric Fluctuations in Patients With Parkinson's Disease, Evaluated With a New, Dedicated Scale
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 31 (actual)
- Sponsor
- University Hospital, Grenoble · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- —
Summary
Retrospective, monocentric, observational study designed to evaluate the effects of Bilateral Subthalamic Nucleus Deep Brain Stimulation (DBS STN) on Neuropsychiatric fluctuations in Patients with Parkinson's Disease (PD)
Detailed description
Pre-operative versus 12-Month Follow-Up analysis of changing in Neuropsychiatric Fluctuations Scale (NFS) score in preoperative versus postoperative MED OFF (during acute withdrawal of dopaminergic therapy) and MED ON (during super-liminal Levodopa dose) conditions. Postoperative evaluations are always performed with DBS turned on and stimulating (STIM ON)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | none (observational study) | DBS |
Timeline
- Start date
- 2020-05-01
- Primary completion
- 2020-07-21
- Completion
- 2020-07-21
- First posted
- 2020-10-29
- Last updated
- 2020-11-02
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04608123. Inclusion in this directory is not an endorsement.