NCT04606212

The Effects of Losartan on Emotion Processing

Losartan Effects on the Emotion Processing in Humans

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: University of Electronic Science and Technology of China · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to investigate the effect of losartan (50mg, single dose) on salience processing

Detailed description

In a double-blind, between-subject, placebo-controlled design the effects of a single dose of losartan (50mg) on salience processing in healthy participants will be examined. The study will adopt a previously validated visual Oddball fMRI paradigm, starting 90 minutes after subjects receive 50mg losartan or placebo. The task requires participants to respond to emotional and novelty oddballs. Neural activity will be assessed by the acquisition of functional magnetic resonance imaging (fMRI) data.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Losartan	administration of losartan (50 mg) (oral)
DRUG	Placebo Oral Tablet	administration of placebo (oral)

Timeline

• Start date: 2020-10-10
• Primary completion: 2021-12-31
• Completion: 2022-03-31
• First posted: 2020-10-28
• Last updated: 2020-10-28

Locations

1 site across 1 country: China