Clinical Trials Directory

Trials / Completed

CompletedNCT04605484

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled, Multiple Dosing Interval, 2-period Study of the Safety, Tolerability and Effectiveness of Adoptively Transferred Posoleuccel (ALVR105) Multivirus-specific T Cells in Kidney Transplant Recipients With Either High or Low Levels of BK Viremia

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
61 (actual)
Sponsor
AlloVir · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare Posoleucel (formerly known as ALVR105; Viralym-M) to placebo in kidney transplant recipients who have high or low levels of BK virus in their blood.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPosoleucel (formerly known as ALVR105) cellsInfusion
BIOLOGICALPlacebo (visually identical to Posoleucel)Infusion

Timeline

Start date
2021-03-22
Primary completion
2022-10-20
Completion
2022-10-20
First posted
2020-10-28
Last updated
2024-05-16
Results posted
2024-05-16

Locations

33 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04605484. Inclusion in this directory is not an endorsement.