NCT04604405

Effects of 650nm Low Energy Light on Human Retina and Choroid Microcirculation

Effect of 650nm Low Energy Light on Macular Microcirculation in Myopia Prevention and Control

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 126 (actual)
• Sponsor: Central South University · Academic / Other
• Sex: All
• Age: 7 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This project is a single-center, prospective, self-controlled clinical study. It intends to select patients with simple medium and low degree myopia as subjects, and apply 650nm low-energy red light irradiation to the retina to observe its effect on macular microcirculation.

Detailed description

A total of 120 subjects are planned to be recruited and divided into 4 groups according to age and intervention, including 30 in the juvenile intervention group, 30 in the juvenile control group, 30 in the adult intervention group and 30 in the adult control group. Two intervention groups received 650nm low-energy red light irradiation treatment with a 650nm low-energy light emitter, twice a day for 3 minutes each time, The subjects were treated and followed up for 3 months. The control group was not treated and followed up for 3 months too. All subjects were followed up before treatment, at the end of the 1st month and at the end of 3rd month. Angio-oct was used as the main examination to observe and record the vascular density and blood perfusion in macular area. Axial length, diopter and OCT were used as secondary observation indexes. At the end of the experiment, the data of the intervention group and the control group were compared

Conditions

• Myopia

Interventions

Type	Name	Description
RADIATION	photobiomodulation	650nm low energy red light eye irradiation

Timeline

• Start date: 2020-09-08
• Primary completion: 2020-10-09
• Completion: 2021-10-02
• First posted: 2020-10-27
• Last updated: 2021-10-15

Locations

1 site across 1 country: China