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UnknownNCT04603573

Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant

Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Fissure Sealant in Newly Erupted Permanent Molars in Group of Egyptian Children : A Randomized Clinical Trial ( Part 1)

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
91 (estimated)
Sponsor
Cairo University · Academic / Other
Sex
All
Age
6 Years – 12 Years
Healthy volunteers
Accepted

Summary

The aim of the present study is determine the cost-effectiveness, clinical-effectiveness, acceptability and adverse effect of resin sealants versus the fluoride varnish for the prevention of dental caries on newly erupted permanent molars.

Detailed description

A Cochrane systematic reviews found low quality evidence supporting Current practice guidelines that recommend the use of Resin based fissure sealant over Fluoride varnish in prevent dental caries. However, they did not address the cost-effectiveness, A more recent systematic review and meta-analysis concluded that no statistical significance difference between Resin based fissure sealant and Fluoride varnish with a high-quality evidence in prevent dental caries. This trial will measure cost effectiveness and clinical effectiveness for resin fissure sealant and fluoride varnish.

Conditions

Interventions

TypeNameDescription
DEVICEfluoride varnish (3M Clinpro White Varnish 5% sodium fluoride )5% Sodium Fluoride Varnish is a fluoride varnish which is applied to tooth surfaces for sealing dentinal tubules and treatment of hypersensitive teeth. The varnish is applied in a thin layer over the tooth with an applicator brush, and moisture from saliva cures the varnish for adhesion to the tooth surface.
DEVICEResin based fissure sealant (3M Clinpro sealant )teeth will be isolated with coton rolls and saliva ejector then etching for pits and fissure then tooth will be washed then apply resin based fissure sealant on occlusal surface. resin fissure sealant is a more sensitive for saliva.

Timeline

Start date
2021-07-10
Primary completion
2022-08-01
Completion
2022-09-01
First posted
2020-10-27
Last updated
2021-08-02

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT04603573. Inclusion in this directory is not an endorsement.