NCT04602845

Remimazolam Tosilate Sedation and Midazolam Sedation in Dental Patients

The Effects of Remimazolam Tosilate Sedation Compared With Midazolam Sedation in Dental Patients: A Double Blind, Prospective , Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: Peking University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Remimazolam Tosilate is a new short-acting benzodiazepines used in sedation. It has the advantages of rapid metabolism, quick recovery without injection pain. This study aims to compared with Midazolam, study whether Remimazolam Tosilate can achieve the same sedation effect with lower side effects on sedation maintenance period, During the recovery period of anesthesia, can Remimazolam Tosilatebe more stable and rapid.

Conditions

• Sedation Complication
• Midazolam
• Remimazolam

Interventions

Type	Name	Description
DRUG	Fentanyl	50ug Fentanyl intravenously
DRUG	Flurbiprofen	50mg Fentanyl intravenously
DRUG	Midazolam	2.5mg midazolam in 2ml normal saline intravenously
DRUG	Remimazolam	3mg Remimazolam in 2ml normal saline intravenously

Timeline

• Start date: 2021-04-01
• Primary completion: 2021-06-30
• Completion: 2021-12-31
• First posted: 2020-10-26
• Last updated: 2022-03-15

Locations

2 sites across 1 country: China