NCT04600648

Sweet Taste Responsiveness in Relation to Insulin, Leptin and Adiposity Among Obese Treatment Seeking Children

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: State University of New York at Buffalo · Academic / Other
• Sex: All
• Age: 8 Years – 14 Years
• Healthy volunteers: Not accepted

Summary

This study will explore whether a relationship exists between insulin and leptin resistance, sweet taste responsiveness, and adiposity.

Detailed description

Compared to healthy weight peers, some reports have shown that they are less sensitive to, or perceptive of, sucrose solutions and sweet foods, whereas others have observed the opposite pattern of findings or no difference at all. Among those seeking weight loss treatment, one investigation found perception and preferences for sweet taste remained unchanged after weight loss, and another observed a decreased ability to distinguish sweet taste from other taste solutions. Given these discrepancies in the literature, the proposed study will explore whether a relationship exists between insulin and leptin resistance, sweet taste responsiveness, and adiposity.

Conditions

• Pediatric Obesity

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Serum insulin level	Measure levels before and after weight loss related to bariatric surgery
DIAGNOSTIC_TEST	Serum Leptin test	Measure levels before and after weight loss related to lifestyle change weight loss

Timeline

• Start date: 2018-09-20
• Primary completion: 2019-08-02
• Completion: 2019-08-02
• First posted: 2020-10-23
• Last updated: 2023-06-26