Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT04599543

IL3 CAR-T Cell Therapy for Patients With CD123 Positive Relapsed and/or Refractory Acute Myeloid Leukemia

Clinical Trial for the Safety and Efficacy of IL3 CAR-T Cell Therapy for Patients With CD123 Positive Relapsed and/or Refractory Acute Myeloid Leukemia

Status
Not Yet Recruiting
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
36 (estimated)
Sponsor
Zhejiang University · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

A Study of IL3 CAR-T Cell Therapy for Patients With CD123 Positive Relapsed and/or Refractory Acute Myeloid Leukemia.

Detailed description

This is a single arm, open-label, single-center study. This study is indicated for relapsed or refractory CD123+ acute myeloid leukemia. The selections of dose levels and the number of subjects are based on clinical trials of similar foreign products. 36 patients will be enrolled. Primary objective is to explore the safety, main consideration is dose-related safety.

Conditions

Interventions

TypeNameDescription
DRUGIL3 CAR T-cellsEach subject receive IL3 CAR T-cells by intravenous infusion

Timeline

Start date
2020-11-15
Primary completion
2023-11-15
Completion
2026-11-15
First posted
2020-10-22
Last updated
2020-10-27

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04599543. Inclusion in this directory is not an endorsement.

IL3 CAR-T Cell Therapy for Patients With CD123 Positive Relapsed and/or Refractory Acute Myeloid Leukemia (NCT04599543) · Clinical Trials Directory