NCT04597463

The Combination of Endometrial Injury and Freeze All Strategy in Women With a History of RIF

The Combination of Endometrial Injury and Freeze All Strategy in Women With a History of Repeated Implantation Failure.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: National and Kapodistrian University of Athens · Academic / Other
• Sex: Female
• Age: 25 Years – 42 Years
• Healthy volunteers: Accepted

Summary

The investigators checked the hypothesis whether endometrial injury performed during the cycle before a frozen embryo transfer in women with RIF can improve pregnancy rates

Detailed description

After a freeze all cycle, participants were divided in two groups: an intervention group (n=30), who underwent endometrial injury before the transfer, and a control group (n=30), who underwent no other intervention. The primary outcome was clinical pregnancy rate, while secondary clinical and laboratory parameters. Baseline and cycle characteristics were also compared between groups.

Conditions

• Endometrial Injury
• Hysteroscopy
• Repeated Implantation Failures

Interventions

Type	Name	Description
PROCEDURE	Endometrial injury	Endometrial injury was performed hysteroscopically after freeze all cycles and during the cycle before the frozen embryo transfer

Timeline

• Start date: 2017-12-02
• Primary completion: 2020-09-02
• Completion: 2020-10-02
• First posted: 2020-10-22
• Last updated: 2020-10-27

Locations

1 site across 1 country: Greece