NCT04596748

Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris

Prospective Randomized Double-Blind Placebo-Controlled Study of Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Integrative Skin Science and Research · Industry
• Sex: All
• Age: 13 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine how probiotics affect sebum production and gut health in those with acne vulgaris.

Detailed description

Probiotics have been shown in previous pilot studies to be helpful in acne and this study aims to examine how the gut microbiome and skin biophysical properties are shifted in those with acne vulgaris. In particular, this study will assess the influence of oral spore based probiotics on the skin sebum production and will assess how probiotics influence the gut microbiome and the blood levels of short chain fatty acids.

Conditions

• Acne Vulgaris

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	Bacillus Subtilis, Bacillus Clausii, Bacillus Coagulans, Bacillus Indicus HU36, MCC 102
DIETARY_SUPPLEMENT	Placebo	Placebo caps

Timeline

• Start date: 2020-05-11
• Primary completion: 2021-03-01
• Completion: 2021-03-01
• First posted: 2020-10-22
• Last updated: 2020-11-24

Locations

1 site across 1 country: United States