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CompletedNCT04596579

SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida

SARS-CoV-2 Immune Surveillance Among a Population Based Sample of Adults in Florida

Status
Completed
Phase
Study type
Observational
Enrollment
1,135 (actual)
Sponsor
H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The overall goal of this study is to understand the immune response (IgG) to SARS-CoV-2 to fill critical knowledge gaps in the natural history of this virus and to inform the development of future infection mitigation efforts. The study team aims to assess the prevalence of circulating IgG antibodies to SARS-CoV-2 and the factors associated with sero-prevalence. These data will be used to estimate the total population that has been exposed to the virus (asymptomatic and symptomatic), the proportion of the population that may be protected by natural immunity, and the proportion that is susceptible. Data obtained from this research will be shared with the Florida Department of Health.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTSARS-CoV-2 Antibody Analysis10 ml of blood will be drawn for antibody analysis. Participants who test SARCS-CoV-2 positive will be invited to participate in follow-up antibody testing at 4 weeks and at 3 months.
DIAGNOSTIC_TESTWeck-cel Swab CollectionA Weck-cel swab will be used to collect secretions from the mucosal epithelium
BEHAVIORALWeb Based QuestionnaireA brief web enabled questionnaire will be administered to collect information related to demographics, SARS-CoV-2 exposure history, past symptoms, comorbidities associates with increased infection and disease risk, as well as immunosuppression status and use to immunosuppressive medications.

Timeline

Start date
2020-10-17
Primary completion
2021-07-25
Completion
2021-07-25
First posted
2020-10-22
Last updated
2022-10-03

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT04596579. Inclusion in this directory is not an endorsement.

SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida (NCT04596579) · Clinical Trials Directory