NCT04596553

Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men

The Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: University of British Columbia · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess which amino acids are affecting acute muscle collagen synthesis in response to supplementation and exercise.

Detailed description

This is a double-blinded, randomized controlled, parallel design study, with 3 treatment groups (placebo, collagen peptide, and essential amino acid). The study will involve 3 visits: a baseline testing/familiarization session, and 2 exercise trials which will include muscle biopsies, blood draws, and the infusion of a tracer isotope in order to measure muscle protein synthesis.

Conditions

• Skeletal Muscle
• Extracellular Matrix
• Amino Acids Metabolism
• Exercise
• Dietary Supplements

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Essential Amino Acid	Immediately following the exercise intervention participants will consume their assigned essential amino acid supplement
DIETARY_SUPPLEMENT	Collagen Peptide	Immediately following the exercise intervention participants will consume their assigned collagen peptide supplement
DIETARY_SUPPLEMENT	Maltodextrin Placebo	Immediately following the exercise intervention participants will consume their assigned maltodextrin supplement

Timeline

• Start date: 2021-01-25
• Primary completion: 2022-02-13
• Completion: 2022-02-13
• First posted: 2020-10-22
• Last updated: 2023-06-13

Locations

1 site across 1 country: Canada