NCT04592848

Female Sexual Function After Cystectomy

Female Sexual Function and Sexual Quality of Life After Cystectomy or Urinary Diversion in Patients With Non-malignant Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 36 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: Female
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Cystectomy with bladder replacement, with or without urinary diversion, is the preferred treatment option for benign pathologies responsible for neurogenic bladder or sphincter dysfunction after failure of conservative treatments. This surgery has both the objective of preventing urological complications and improving quality of life. We know that women are especially affected by these conditions, as demonstrated by the high prevalence of demyelinating diseases such as multiple sclerosis in this population. Patients are often young and sexually active before the surgery. Despite the existence of validated evaluation tools since the early nineties, there is poor data exploring effects of invasive procedures such as cystectomy on sexual activity and quality of sexual life in female patients. Indeed, existing literature largely focuses on sexual function in male population after cystectomy for urothelial cancer. Data on sexual function after stoma formation in women with colorectal cancer show a significant change after the surgery, partly due to body image issues. We can easily suppose that there's also an important impact of cystectomy that may affect sexual quality of life. Thus, the objective of the study is to assess sexual function and determine factors that may influence sexual quality of life in female patients following cystectomy or urinary diversion.

Conditions

• Sexual Activity

Interventions

Type	Name	Description
OTHER	Questionnaires	Four Questionnaires in French will be sent to participants : * 1 questionnaire about sexual and urinary symptoms before and after the surgery ; * 1 validated questionnaire "Female Sexual Function Index" to assess sexual function over the past 4 weeks ; * 1 validated questionnaire "Body Image Scale" to assess body image during the past week ; * 1 validated questionnaire "Stoma Quality of Life", only for patients with incontinent urostomy. If the questionnaires are not returned 15 days after sending, a follow-up phone call will be made by one of the investigators. The data collection will include both the answers to the questionnaires and the patients' computerized medical data: * Pathology responsible for the urological disorders and date of onset of the disorders * Date and Type of surgery performed * Patient's age at the time of surgery * Post-operative complications within one month of surgery

Timeline

• Start date: 2021-01-21
• Primary completion: 2021-04-15
• Completion: 2021-04-15
• First posted: 2020-10-19
• Last updated: 2022-04-29

Locations

1 site across 1 country: France