Trials / Completed
CompletedNCT04592276
The Effects of Lactobacillus Plantarum PS128 in Self-Reported Insomniacs
The Effects of Lactobacillus Plantarum PS128 on Depression, Anxiety, Cerebral Rhythms, Autonomic Nervous System Function and Sleep Patterns in Self-Reported Insomniacs
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- National Yang Ming Chiao Tung University · Academic / Other
- Sex
- All
- Age
- 20 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
To determine whether PS128 (1) reduces the severity of anxiety and depressive symptoms, (2) adjusts autonomic nervous system functioning, and (3) improves sleep quality.
Detailed description
Forty participants with self-reported insomnia between 20 and 40 years old were randomly assigned to two groups, the PS128 and a placebo group, under the double-blind trial. Participants took two capsules with or without PS128 after dinner for 30 days. Study measures included subjective depressive symptoms, anxiety and sleep questionnaires, and miniature polysomnography (miniature-PSG) recordings at baseline and on the 15th and 30th days after taking capsules.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | PS128 | Participants took two capsules with PS128 after dinner for 30 days. |
| DIETARY_SUPPLEMENT | placebo | Participants took two capsules without PS128 after dinner for 30 days. |
Timeline
- Start date
- 2018-10-11
- Primary completion
- 2019-12-27
- Completion
- 2019-12-27
- First posted
- 2020-10-19
- Last updated
- 2022-07-21
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT04592276. Inclusion in this directory is not an endorsement.