Trials / Unknown
UnknownNCT04590482
Letrozole Pretreatment With Misoprostol Induction of Abortion in First Trimester Missed Abortion
Use of Letrozole Pretreatment With Misoprostol for Induction of Abortion in First Trimester Missed Abortion
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 110 (estimated)
- Sponsor
- Shereen Rady Abou El-fetouh · Academic / Other
- Sex
- Female
- Age
- 18 Years – 42 Years
- Healthy volunteers
- Accepted
Summary
this study will compare the efficacy of using letrozole pre treatment before misoprostol versus using misoprostol only in the induction of first trimester missed abortion.
Detailed description
Intervention type: drug Intervention name: letrozole then misoprostol Description :letrozole 2.5mg twice per day for 2days then misoprostol 800mcg for all patients to induce abortion Arm group label:study group Intervention type :drug Intervention name:placebo then misoprostol Description : placebo for 2days then 800mcg misoprostol to all patients to induce abortion Arm group label: control group
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | letrozole | Letrozole 2.5 mg each 12 hours for 2 days followed by vaginal misoprostol 800 mcg for induction of abortion |
| DRUG | placebo | placebo given twice daily for 2 days followed by 800mcg misoprostol vaginally to induce abortion |
Timeline
- Start date
- 2020-11-15
- Primary completion
- 2021-03-16
- Completion
- 2021-05-08
- First posted
- 2020-10-19
- Last updated
- 2020-10-29
Source: ClinicalTrials.gov record NCT04590482. Inclusion in this directory is not an endorsement.