NCT04580823

Heart and Kidney Ketones Metabolism

Exogenous Ketone Salt on Heart and Kidney Ketone Metabolism Measured by Positron Emission Tomography

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Université de Sherbrooke · Academic / Other
• Sex: All
• Age: 45 Years – 64 Years
• Healthy volunteers: Accepted

Summary

Participants will undergo 3 Positron Emission Tomography (PET) scans in 3 different conditions : 1. Fasting without exogenous ketone salt 2. Fasting with exogenous ketone salt supplement 3. Post-Prandial with exogenous ketone salt supplement.

Detailed description

This study will help to quantify heart and kidney ketone uptake with or without an exogenous ketone salt with or without food intake in middle-aged adults. Participants will have 3 different PET scan to perform : 1. Fasting without exogenous ketone salt 2. Fasting with exogenous ketone salt supplement 3. Post-Prandial with exogenous ketone salt supplement.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fasting with exogenous ketone salt supplement	Participants will have to take 2 doses of supplement, one 75 minutes before the scan and one 30 minutes before the scan.
DIETARY_SUPPLEMENT	Post-Prandial with exogenous ketone salt supplement	Participants will have to take 2 doses of supplement, one 75 minutes before the scan and one 30 minutes before the scan and they will have a liquid meal 20 minutes before the scan.

Timeline

• Start date: 2020-10-15
• Primary completion: 2022-08-15
• Completion: 2023-01-15
• First posted: 2020-10-08
• Last updated: 2023-07-19

Locations

1 site across 1 country: Canada