Clinical Trials Directory

Trials / Completed

CompletedNCT04579094

Prevalence and Risk Factors for the Carriage of Bacteria and Clostridioid in Elderly Dependent Persons

Prevalence and Risk Factors for the Carriage of Multi- and Highly Resistant Bacteria and Clostridioid Difficile Toxigenic in Residents and Healthcare Workers in Nursing Home (PREMS)

Status
Completed
Phase
Study type
Observational
Enrollment
492 (actual)
Sponsor
Centre Hospitalier Universitaire de Nīmes · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Brief summary : Very few studies have evaluated the prevalence of multi-drug resistant (MDR), highly resistant emerging bacteria and Clostridioides difficile toxinogenic (CDt) in residents and in healthcare workers (HCW) in nursing home (NH). Most of study were conducted in acute care services and were limited to specific bacterial species. Hypothesis : The carriage of MDR bacteria in resident may be a risk factor for an outbreak in NH or in healthcare facility. Primary outcome: The objective of this study is to estimate the prevalence for carriage of MDR bacteria and CDt in residents in NH. Secondary outcomes: * Estimate the prevalence for carriage of MDR bacteria and CDt toxigenic in HCW in NH. * Identify the risk factors for carriage of MDR bacteria and CDt in residents in nursing home * Identify the risk factors for carriage of MDR bacteria and CDt in healthcare workers in NH * Evaluate the presence of cross-transmission of MDR bacteria and CDt in one or several NH * Evaluate the association between the presence of cross-transmission of MDR bacteria and CDt in a NH and the management of infection control * Establishment a collection of stool samples

Conditions

Interventions

TypeNameDescription
OTHERFeces sampling at inclusion (J0)Feces sampling at inclusion (J0)

Timeline

Start date
2022-05-25
Primary completion
2024-09-30
Completion
2024-09-30
First posted
2020-10-08
Last updated
2025-05-28

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT04579094. Inclusion in this directory is not an endorsement.