NCT04577222

The Ability of Adipose Flap Over the NVB to Improve Sexual and Urinary Function Following Radical Prostatectomy

The Ability of Adipose Flap Over the NVB to Improve Sexual and Urinary Function Following Radical Prostatectomy; a Randomized Control Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Rabin Medical Center · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

Despite technological advances, incontinence and impotence remain significant side effects of radical prostatectomy (RP). Strategies have been developed to reduce the injury to the erection nerves (i.e. neurovascular bundle - NVB)during surgery to further improve functional outcomes after RP. Adipose tissue is known for its stabilizing and even healing potential. These features include reducing the inflammatory process and improving blood supply to an injured nerve. We hypothesized that covering the NVB with periprostatic fat during surgery may potentially improve neural recovery and enhance functional recovery after RP. We sought to examine our hypothesis in a randomized controlled trial.

Conditions

• Prostate Cancer
• Erectile Dysfunction
• Urinary Incontinence

Interventions

Type	Name	Description
PROCEDURE	Technical modification during radical prostatectomy	Covering the NVB with fat

Timeline

• Start date: 2018-04-15
• Primary completion: 2022-04-15
• Completion: 2022-07-15
• First posted: 2020-10-06
• Last updated: 2020-10-06

Locations

1 site across 1 country: Israel