Trials / Completed
CompletedNCT04577170
Pulsatility Index, Vasomotor Reactivity and Leukoencephalopathy in Fabry Patients
Association of the Pulsatility Index and Vasomotor Reactivity With White Matter Lesions in Brain MRI of Fabry Disease Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 45 (actual)
- Sponsor
- National and Kapodistrian University of Athens · Academic / Other
- Sex
- All
- Age
- 16 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
We hypothesize that Fabry disease - FD is associated with elevated vascular resistance induced by cerebral small-vessel disease, indicating increased distal resistance to blood flow. The findings of this study may be used as a precursor for neuroimaging manifestations related to stroke in FD patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography | Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography will be performed in consecutive FD patients. All TCD and TCCD studies will be performed by stroke neurologists experienced in vascular sonography. |
Timeline
- Start date
- 2020-11-20
- Primary completion
- 2022-07-01
- Completion
- 2023-01-20
- First posted
- 2020-10-06
- Last updated
- 2023-11-09
Locations
1 site across 1 country: Greece
Source: ClinicalTrials.gov record NCT04577170. Inclusion in this directory is not an endorsement.