NCT04576013

Peripheral Nerve Stimulation to Improve Upper Extremity Function After Severe Stroke

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Kentucky · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Subjects will receive non-invasive stimulation of nerves on their arm and intensive motor training of their arm. The timing of the stimulation in relation to the training will vary by group.

Detailed description

This study will look at the differences in improvement of hand and arm function when nerve stimulation is applied at different times in relation to motor training. The nerve stimulation, called peripheral nerve stimulation (PNS), is non-invasive and painless. Subjects in the study may receive strong or mild PNS. Subjects will also vary by whether PNS is delivered for 2 hours before the 2 hours of motor training, or during the 2 hours of motor training. Which level of stimulation and its timing will be determined randomly for each subject.

Conditions

• Stroke

Interventions

Type	Name	Description
DEVICE	Peripheral nerve stimulation (PNS)	Non-invasive stimulation is applied to 3 nerves of the arm. The stimulation will be set at a level that is not painful or uncomfortable.
BEHAVIORAL	Intensive upper extremity motor training

Timeline

• Start date: 2016-02-23
• Primary completion: 2021-02-22
• Completion: 2021-02-22
• First posted: 2020-10-05
• Last updated: 2021-02-25

Locations

1 site across 1 country: United States