Trials / Recruiting
RecruitingNCT04571658
NEPTUNE Match Study
Implementing Precision Medicine for Glomerular Diseases in the Nephrotic Syndrome Study Network (NEPTUNE)
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 375 (estimated)
- Sponsor
- University of Michigan · Academic / Other
- Sex
- All
- Age
- 1 Year – 80 Years
- Healthy volunteers
- Not accepted
Summary
NEPTUNE Match is an additional opportunity offered to NEPTUNE study participants to prospectively recruit and communicate patient-specific clinical trial matching with kidney patients and their physician investigators.
Detailed description
This is a prospective, open-label study testing the ability to effectively communicate patient-specific clinical trial matching with kidney patients and clinician investigators. The study consists of four components: 1. Recruitment of participants from the NEPTUNE observational cohort study 2. Generation of participant profile-trial match assessment using data from the NEPTUNE observational study and profiling units by the NEPTUNE Molecular Nephrology Board 3. Establishing and testing a framework to communicate disease-trial drug mechanism matching with investigators and patients 4. Retrospective comparison of kidney health outcomes in subjects enrolled in trials that aligned with their match vs. trial subjects with mis-aligned or unknown match alignment.
Conditions
- Nephrotic Syndrome in Children
- Focal Segmental Glomerulosclerosis
- Minimal Change Disease
- Minimal Change Nephrotic Syndrome
- Membranous Nephropathy
- FSGS
- MCD
- MCD - Minimal Change Disease
- Alport Syndrome
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Communication | The NEPTUNE Match study includes an interdisciplinary Communication Team that will translate findings from the Molecular Nephrology Board (MNB) to inform patients of the matching assessment with ongoing clinical trials. This team has considerable experience with conveying complex biomedical research information to patients and families and includes experts in precision nephrology, nephrology patient \[adult and pediatric\] communication, and health education. |
Timeline
- Start date
- 2022-05-02
- Primary completion
- 2029-06-30
- Completion
- 2029-06-30
- First posted
- 2020-10-01
- Last updated
- 2026-02-17
Locations
16 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT04571658. Inclusion in this directory is not an endorsement.