Trials / Completed
CompletedNCT04570540
Obesity in Sleep Medicine - Focusing on OHS Phenotypes
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 82 (actual)
- Sponsor
- Wissenschaftliches Institut Bethanien e.V · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
This study focuses on a comprehensive examination of obese patients with sleep-related breathing disorders including patients with OSA, sleep hypoventilation and OHS. The aim of this study is to (1) evaluate characteristics of and differences between severity levels of obesity-related breathing disorders, (2) discuss pathophysiological variables associated with hypoventilation during sleep or at daytime and (3) find functional parameters indicating sleep hypoventilation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Sleep Study | Full-night attended in-lab polysomnography with accompanying transcutaneous capnometry |
| DIAGNOSTIC_TEST | Pulmonary Function Test | Bodyplethysmographic assessment |
| DIAGNOSTIC_TEST | Hypercapnic ventilatory response | Measurement of hypercapnic ventilatory response based on the method described by Read in 1967, using a rebreathing bag |
| DIAGNOSTIC_TEST | Cardiopulmonary Exercise Test | Symptom-limited cardiopulmonary exercise test with a ramp protocol according to the ATS/ACCP and ERS recommendations |
Timeline
- Start date
- 2014-04-24
- Primary completion
- 2019-09-10
- Completion
- 2019-09-10
- First posted
- 2020-09-30
- Last updated
- 2020-09-30
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT04570540. Inclusion in this directory is not an endorsement.