Clinical Trials Directory

Trials / Completed

CompletedNCT04569188

Convalescent Plasma in COVID-19 Elderly Patients

Real-time Evaluation of Safety and Efficacy of Convalescent Plasma Units Transfused to Elderly Patients With COVID-19

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
21 (actual)
Sponsor
Azienda Socio Sanitaria Territoriale di Mantova · Academic / Other
Sex
All
Age
65 Years
Healthy volunteers
Not accepted

Summary

The trend of the spread of the COVID-19 pandemic demonstrates in Lombardy, starting from 28.03.2020, a slowdown in the exponential phase of infections and the probable reaching of a plateau phase. However, a marked increase in infections was observed in the so-called "protected structures" such as nursing homes (RSA), both in health staff and in the residents of such facilities. The observed percentage of lethality, according to the more recent data provided by the National Institute of Health, is very high especially among residents. For these reasons, the city Hospital (ASST) of Mantua , already involved in the use of hyperimmune plasma as a therapy for COVID-19, designed this study in order to evaluate RSA patients and to identify the cases eligible for this treatment.

Detailed description

For a detailed description of the study, see the attached protocol

Conditions

Interventions

TypeNameDescription
BIOLOGICALConvalescent plasmaCOVID-19 elderly patients treated with convalescent plasma

Timeline

Start date
2020-05-15
Primary completion
2020-08-15
Completion
2020-09-03
First posted
2020-09-29
Last updated
2020-10-05

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT04569188. Inclusion in this directory is not an endorsement.

Convalescent Plasma in COVID-19 Elderly Patients (NCT04569188) · Clinical Trials Directory