Clinical Trials Directory

Trials / Completed

CompletedNCT04568499

Presenting Nutrition Characteristics, Comorbidities and Outcomes of COVID-19 in African Humanitarian Settings

Presenting Nutrition Characteristics, Comorbidities and Outcomes of COVID-19 in African Humanitarian Settings: a Prospective Cohort Study in South Sudan and DRC

Status
Completed
Phase
Study type
Observational
Enrollment
592 (actual)
Sponsor
Johns Hopkins Bloomberg School of Public Health · Academic / Other
Sex
All
Age
5 Years
Healthy volunteers
Not accepted

Summary

This study will characterize risk factors for poor COVID-19 outcomes (hospitalization, death) and clinical progression of hospitalized COVID-19 patients in South Sudan and Eastern Democratic Republic of the Congo.

Detailed description

A prospective cohort design will be used to follow suspected, probable, and confirmed COVID-19 cases presenting for care at International Medical Corp \[supported\] health facilities in Juba, South Sudan and the Kivus in Eastern Democratic Republic of the Congo (DRC). This research seeks to assess risk factors for poor outcomes and characterize clinical disease progression of COVID-19 cases in resource-poor humanitarian contexts in Africa. Specifically, this study aims to characterize risk factors for poor COVID-19 outcomes, including both co-morbidities with evidence from high income settings, as well as prevalent conditions in humanitarian settings (e.g., acute malnutrition, malaria, HIV) for which data is not yet available. This research also aims to determine how the progression of confirmed COVID-19 cases in resource-poor African settings may differ from other settings where data are available.

Conditions

Timeline

Start date
2020-11-27
Primary completion
2021-06-30
Completion
2021-09-30
First posted
2020-09-29
Last updated
2021-11-03

Locations

3 sites across 2 countries: Democratic Republic of the Congo, South Sudan

Source: ClinicalTrials.gov record NCT04568499. Inclusion in this directory is not an endorsement.