NCT04563429

Vitamin A for BPD Prevention

Vitamin A Oral Supplementation as a Preventive Treatment for Chronic Lung Disease Among Infants Born Before 29 Weeks of Gestation.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Sheba Medical Center · Other Government
• Sex: All
• Age: 2 Days – 5 Days
• Healthy volunteers: Not accepted

Summary

Chronic bronchopulmonary dysplasia (BPD) is a very common complication in preterm infants born at a young gestational age, and is a serious disease that impairs respiratory long-term outcome and is associated with higher-frequency neurodevelopmental injury. Lowering the incidence of BPD may improve the health of the preterm babies and neurodevelopmental delay of preterm infants.Vitamin A deficiency may be one of the factors associated with the development of BPD in preterm infants. According to the literature, oral vitamin A administration can lower the incidence of BPD. In our study we plan to give 5000 units of retinol / dose / day, every day for 28 days.

Conditions

• The Relationship Between Oral Vitamin A Administration and the Incidence of BPD in Preterm Infants Born Before Week 29 of Pregnancy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral Vitamin A	Oral administration of 5000 EU of Vitamin A during first 28 days of life

Timeline

• Start date: 2020-10-01
• Primary completion: 2022-10-01
• Completion: 2023-10-01
• First posted: 2020-09-24
• Last updated: 2020-09-24