NCT04563234

Perioperative Cognitive Training in Thoracic Surgery

Perioperative Cognitive Flexibility Training for the Prevention of Persistent Pain After Thoracic Surgery

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

More than 30% of patients undergoing thoracic surgical procedures develop persistent post-surgical pain (PPSP), which results in impaired functioning, diminished quality of life, and increased risk of chronic opioid use. The proposed project aims to determine whether a prospective, randomized, controlled study of smartphone-based perioperative cognitive flexibility training will reduce the incidence of PPSP in high-risk individuals undergoing thoracic surgery.

Conditions

• Pain, Postoperative
• Cognitive Function Abnormal
• Lung Cancer

Interventions

Type	Name	Description
BEHAVIORAL	COFLEX neurocognitive training	The COFLEX training group will then be provided with the cognitive training module and participants will be required to complete a targeted 30-minute daily training until the day of surgery, and then after the surgery, for a total of 6 weeks.
BEHAVIORAL	Crossword puzzles	The control (crossword puzzles) group will be given a training module, where they can access crossword puzzles on the same platform, and can do puzzles whenever they desire over the 6-week time period.

Timeline

• Start date: 2023-06-30
• Primary completion: 2024-07-31
• Completion: 2024-07-31
• First posted: 2020-09-24
• Last updated: 2023-01-30