Trials / Unknown
UnknownNCT04561440
Copy Number Variation in Prenatal Diagnosis
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 16,000 (estimated)
- Sponsor
- YiYang Zhu · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
An observed study is aim to map the CNVs distribution in human genome of Chinese prenatal population. Setting: Prenatal diagnosis center of Taizhou City, Zhejiang Province Patient: total cases of pregnant women needed prenatal genetic diagnosing Methods: karyotype was performed with combined of molecular and cytogenic protocol. Subgroup: molecular karyotyping performed by genomic Chip (CMA) or NGS, the latter including cnv-seq and NIPT. Main outcome: comparison of CNVs distributions in subgroups. Second outcome: comparison of CNVs distributions in demographic dates.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | molecular karyotyping | performed by NGS or CMA chip |
Timeline
- Start date
- 2016-12-01
- Primary completion
- 2020-12-30
- Completion
- 2020-12-30
- First posted
- 2020-09-23
- Last updated
- 2020-09-23
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04561440. Inclusion in this directory is not an endorsement.