Clinical Trials Directory

Trials / Unknown

UnknownNCT04558853

Clinical Study of Autologous Natural Killer Cells in Multiple Myeloma

A Safety Study of CellProtect, an Autologous ex Vivo Expanded and Activated Natural Killer (NK) Cell Product, in Patients With Multiple Myeloma

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
12 (estimated)
Sponsor
Karolinska University Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Multiple Myeloma (MM) is a lethal disease and at present no available treatment method seems to prevent the disease from progressing or relapsing in the long term. NK cells have a relatively high cytotoxic capacity and an anti tumour effect, suggesting a potential as a treatment of MM.This is a phase I, first-in-human, therapeutic exploratory study, where no benefits for the patients can be guaranteed. However, the theoretical implication is that the infused cells may have a positive antitumour effect for the participating individuals.

Conditions

Interventions

TypeNameDescription
DRUGautologous NK cellsAutologous ex vivo expanded and activated NK cells

Timeline

Start date
2014-01-01
Primary completion
2021-12-31
Completion
2022-12-31
First posted
2020-09-22
Last updated
2021-02-17

Locations

1 site across 1 country: Sweden

Source: ClinicalTrials.gov record NCT04558853. Inclusion in this directory is not an endorsement.