NCT04558697

Use of Vagitories Based on St. John's Wort, Tea Tree Oil and Shepherd's Purse in the Treatment of Vaginal Inflammation

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 210 (actual)
• Sponsor: University of Sarajevo · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

There are more and more herbal preparations that are used for the purpose of treatment and improvement of the clinical picture of vaginitis by patients themselves, but also by healthcare professionals. Plant species, St. John's wort, chamomile, calendula, yarrow, shepherd's purse and tea tree oil are well known for there anti-inflammatory, antimicrobial and wound healing activity. This paper presents the results of a clinical study in which three herbal formulations/vagitories, based on extracts of above mentioned plant species, were investigated for their effectiveness on non-specific vaginitis. This was randomized controlled clinical study that included 210 women with diagnosed non-specific vaginitis. Patients were divided into two basic groups, women in reproductive stage and postmenopausal stage. Three subgroups, containing approximately 30 patients each, received one of three vagitorie formulations for 5 days during which the effects on subjective and objective symptoms were monitored.

Conditions

• Non Specific Vaginitis

Interventions

Type	Name	Description
DRUG	Shepherd's Purse extractum oleosum vagitories	Shepherd's Purse extractum oleosum vagitories will be administered once daily for 5 days
DRUG	Tea tree oil vagitories	Tea tree oil vagitories will be administered once daily for 5 days
DRUG	Hyperici extractum oleosum vagitories	Hyperici extractum oleosum vagitories will be administered once daily for 5 days
DRUG	Vagitories - Probiotic	Vagitories - Probiotic will be administered once daily for 5 days

Timeline

• Start date: 2019-03-21
• Primary completion: 2019-06-21
• Completion: 2019-09-30
• First posted: 2020-09-22
• Last updated: 2020-09-22

Locations

1 site across 1 country: Bosnia and Herzegovina