NCT04552522

Immunological Response After Shrimp Oral Immunotherapy Treatment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 12 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Oral immunotherapy is effective in desensitized food allergy. Shrimp allergy is increasing in Thailand. So the purpose of our study is to determine level of specific immunoglobulin E antibodies to shrimp, Immunoglobulin G4 and immunoblot analysis in shrimp allergy patients after shrimp oral immunotherapy.

Detailed description

All subject in this study were sensitized to shrimp. All patient was clinically evaluated, with focus on shrimp allergy by medical history, medical examination and gold standard oral food challenge test. Compare oral immunotherapy to shrimp and shrimp avoidance. Blood sample was taken for baseline determination of immunoglobulin E antibodies to shrimp. The primary outcome was the specific immunoglobulin E antibodies to shrimp,Immunoglobulin G4 and immunoblot analysis in case that oral immunotherapy.

Conditions

• Allergy to Shrimp
• Immunotherapy

Interventions

Type	Name	Description
OTHER	shrimp allergy with intend to eat shrimp	shrimp allergy with intend to eat shrimp and treat with oral immunotherapy

Timeline

• Start date: 2020-08-28
• Primary completion: 2024-10-31
• Completion: 2024-12-30
• First posted: 2020-09-17
• Last updated: 2026-04-03
• Results posted: 2026-04-03

Locations

1 site across 1 country: Thailand