Clinical Trials Directory

Trials / Completed

CompletedNCT04552470

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06882961 in Japanese Adults With Type 2 Diabetes Mellitus

AN 8-WEEK PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, PARALLEL GROUP STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF TWICE DAILY PF-06882961 ADMINISTRATION IN JAPANESE ADULTS WITH TYPE 2 DIABETES MELLITUS

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
37 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
20 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This is a Phase 1, randomized, double blind (sponsor open), parallel, placebo controlled, twice daily oral dosing study of PF 06882961 in adult Japanese participants with T2DM inadequately controlled on diet and exercise alone.

Conditions

Interventions

TypeNameDescription
DRUGPlacebo3 matching placebo tablets taken twice a day (BID)
DRUGPF-06882961Participants will be randomized to one of 3 active doses (40, 80, or 120 mg), taking 3 tablets twice daily for 8 weeks.

Timeline

Start date
2020-10-26
Primary completion
2021-03-25
Completion
2021-03-25
First posted
2020-09-17
Last updated
2022-03-11
Results posted
2022-03-11

Locations

1 site across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT04552470. Inclusion in this directory is not an endorsement.