NCT04551001

Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy

Randomized Controlled Trial Investigating Cold Snare aNd Forcep polypectomY Among Small POLYPs in Rates of Complete Resection: the TINYPOLYP Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 181 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps \<=3mm during colonoscopy.

Detailed description

The details of the proposed study are as follows: 1. Experimental group: using cold forceps for polyps \<=3mm of the colon 2. Control group: using cold snare for polyps \<=3mm of the colon 3. Methods: 1. Colonoscopy will be performed in the same standard of care manner as if no study was taking place. 2. If polyps \<=3mm are identified, the endoscopist is randomized to performing polypectomy with cold forcep or cold snare. 3. After removal of the polypectomy, two biopsies are performed at the margin of the polypectomy site to identify residual lesion. 4. The polyp as well as well as the two biopsies are reviewed by a pathologist.

Conditions

• Colo-rectal Cancer
• Polyp of Colon
• Adenomatous Polyp of Colon

Interventions

Type	Name	Description
PROCEDURE	Cold forcep polypectomy	Removal of appropriate polyps using cold forceps until no polyp visible under white light. Two additional biopsies performed at margins of polypectomy site.
PROCEDURE	Cold snare polypectomy	Removal of appropriate polyps using cold snare until no polyp visible under white light. Two additional biopsies performed at margins of polypectomy site.

Timeline

• Start date: 2020-09-16
• Primary completion: 2021-10-15
• Completion: 2021-11-20
• First posted: 2020-09-16
• Last updated: 2022-05-17

Locations

1 site across 1 country: United States