NCT04550650

Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: Somogy Megyei Kaposi Mór Teaching Hospital · Academic / Other
• Sex: All
• Age: 35 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Different therapies can improve clinical and motor symptoms of multiple sclerosis (MS) similarly, but studies comparing the effects of different exercise therapies on clinical and motor outcomes are scant. We compared the effects of exergaming (EXE), balance (BAL), cycling (CYC), proprioceptive neuromuscular facilitation (PNF), and a standard care wait-listed control group (CON) on clinical and motor symptoms and quality of life (QoL) in people with MS (PwMS). Methods: PwMS (n = 68, 90% female; age, 47.0 yr; Expanded Disability Status Scale score 5-6) were randomized into five groups. Before and after the interventions (five times a week for 5 wk), PwMS were tested for MS-related clinical and motor symptoms (Multiple Sclerosis Impact Scale-29 (MSIS-29), primary outcome), QoL (EuroQol Five Dimensions Questionnaire), symptoms of depression, gait and balance ability (Tinetti Assessment Tool), static and dynamic balance and fall risk (Berg Balance Scale), walking capacity (6-min walk test), and standing posturography on a force platform. Patients were followed up for 2 years after 5 weeks of intensive care. Tests are performed every six months.

Conditions

• Multiple Sclerosis, Chronic Progressive
• Multiple Sclerosis, Primary Progressive

Interventions

Type	Name	Description
OTHER	Training groupe	Using virtual training
OTHER	PNF	PNF technique was used
OTHER	Spinning grp	They only worked with spinning bikes.
OTHER	Balance	Balance development was done

Timeline

• Start date: 2018-04-06
• Primary completion: 2020-04-06
• Completion: 2020-09-01
• First posted: 2020-09-16
• Last updated: 2022-04-05

Locations

1 site across 1 country: Hungary