NCT04547569

Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning

Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning fMRI Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

These studies test the hypothesis that frontal areas of the brain participate in the cortical networks involved in the somotosensory processing that happens during speech motor learning.

Detailed description

This work aims to study the role of sensory systems in human motor learning and specifically addresses the involvement of somatosensory cortical networks in motor learning of speech. Previous studies in the literature have highlighted the plasticity of cortical sensory networks, notably the primary and secondary somatosensory cortex and the ventral premotor cortex, during motor learning tasks. The present project focuses on the somatosensory region with connections to the sensorimotor regions of the frontal and parietal cortex. We propose to use neuroimaging (fMRI), in order to verify which areas in the prefrontal cortex are part of the sensorimotor network used in the learning of speech motor tasks in humans. Subjects will be tested in the fMRI scanner while performing either a behavioral task in which the auditory feedback of their own speech is altered or while performing a vibrotactile discrimination task.

Conditions

• Speech
• Motor Activity

Interventions

Type	Name	Description
BEHAVIORAL	Speech adaptation	Sensorimotor adaptation in speech
BEHAVIORAL	Vibrotactile Discrimination	Vibrotactile Discrimination
OTHER	fMRI	fMRI measurement of brain activity
BEHAVIORAL	Speech production	Speech production task

Timeline

• Start date: 2020-10-20
• Primary completion: 2021-07-06
• Completion: 2021-07-06
• First posted: 2020-09-14
• Last updated: 2022-06-01

Locations

1 site across 1 country: France