Trials / Unknown
UnknownNCT04547114
Breath Analysis for SARS-CoV-2 in Infected and Healthy Subjects
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (estimated)
- Sponsor
- Klinikum Bayreuth GmbH · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Recently published studies could demonstrate that detection of specific biomarkers in breath could be applied for the diagnosis of SARS-CoV-2.
Detailed description
In this study we want to address the sensitivity and specificity of breath analysis by MCC-IMS in the context of SARS-CoV-2 detection from PCR- proven infected and non-infected subjects. Therefore nasal breath will be aspirated for 10 seconds during normal respiration by a foam cuffed oxygen catheter connected via a 0.22μm filter and a line into the MCC-IMS and directly analyzed without any pre-analytic procedures. The during the proof-of-concept study derived significant peaks for volatile organic compounds will be used for discrimination in a point-of-care approach.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Multicapillary column coupled ion mobility spectrometry | sampling of nasal air via a foam cuffed oxygen catheter |
Timeline
- Start date
- 2020-09-14
- Primary completion
- 2020-12-31
- Completion
- 2021-04-30
- First posted
- 2020-09-14
- Last updated
- 2020-09-14
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT04547114. Inclusion in this directory is not an endorsement.