NCT04545801

Ketamine for Analgesia After Cesarean Section

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Mongi Slim Hospital · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.

Detailed description

In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia. The patients were randomized in two groups: * Group Ketamine: these patients recieved 0.25 mg/kg of Ketamin intravenously 5 minutes after the spinal anesthesia. * Group Placebo: recieved 20 ml of normal saline solution intravenously 5 minutes after the spinal puncture. The investigators recorded intra demographic, intraoperative and post operative data. The main outcome was the analgesic score: the visual analog scale (VAS). dynamic VAS was also monitored at 24 hours post operatively.

Conditions

• Cesarean Section
• Postoperative Pain

Interventions

Type	Name	Description
DRUG	0.25 mg/kg of Ketamine	patients will recieve 0.25mg/kg of ketamine intravenously 5 min after spinal anesthesia
DRUG	20ml of normal saline solution	20ml of normal saline solution intravenously 5 minutes after spinal anesthesia

Timeline

• Start date: 2019-01-01
• Primary completion: 2019-03-31
• Completion: 2019-04-30
• First posted: 2020-09-11
• Last updated: 2020-09-16

Locations

1 site across 1 country: Tunisia