Clinical Trials Directory

Trials / Completed

CompletedNCT04542135

Sulindac and Breast Density in Women at Risk of Developing Breast Cancer

Double-blind, Randomized Phase II Clinical Trial of Sulindac for Reducing Breast Density in Postmenopausal Women at Risk of Developing Breast Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
62 (actual)
Sponsor
Alison Stopeck · Academic / Other
Sex
Female
Age
35 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to determine if sulindac at a dose of 150 mg twice a day for 12 months reduces breast density in postmenopausal women at elevated risk of breast cancer when compared to a placebo control.

Conditions

Interventions

TypeNameDescription
DRUGSulindac PillRandomized participants will receive either 150 mg oral sulindac twice daily.
DRUGPlaceboplacebo pills twice daily

Timeline

Start date
2020-11-20
Primary completion
2025-04-22
Completion
2025-05-19
First posted
2020-09-09
Last updated
2025-06-03

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04542135. Inclusion in this directory is not an endorsement.