NCT04542018

Effects of Low FODMAP Diet on Colonic Epithelial Physiology in Diarrhea-predominant Irritable Bowel Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This research is studying whether changing an individual's diet may have an impact as a treatment or outcome for Irritable Bowel Syndrome (IBS). This research will show if diet might play a role in triggering changes that may cause IBS. This study is being done to learn if a low FODMAP (fermentable, oligosaccharides, disaccharides, monosaccharides, and polyols) diet causes changes in the colon lining which mediates improvement in IBS symptoms.

Conditions

• Irritable Bowel Syndrome

Interventions

Type	Name	Description
OTHER	a low FODMAP diet for 4 weeks	low FODMAP diet for 4 weeks

Timeline

• Start date: 2020-08-03
• Primary completion: 2024-05-15
• Completion: 2024-05-15
• First posted: 2020-09-09
• Last updated: 2025-07-30
• Results posted: 2025-07-30

Locations

2 sites across 1 country: United States