NCT04538183

Use Test: Dermowas Body Lotion pH 4 vs. pH 5.8

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Dr. August Wolff GmbH & Co. KG Arzneimittel · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The objective of the study was to examine whether normalizing of the pH by acidification through topical treatment helps to strengthen the skin barrier, to induce epidermal differentiation and to reduce inflammation in healthy individuals.

Detailed description

Previous studies have shown that an emollient adjusted to pH 4 has favorable effects to the skin of aged individuals. The objective of the study was to examine whether normalizing of the pH by acidification through topical treatment helps to strengthen the skin barrier, to induce epidermal differentiation and to reduce Inflammation. The effect of a cosmetic oil-in-water (O/W) emulsion adjusted to pH 4 in comparison to the same emulsion adjusted to pH 5.8 on the integrity of the skin barrier and the mechanical stability was examined in healthy volunteers from age 18 to 75 years.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	WO 5000	WO 5000
OTHER	WO 5001	WO 5001

Timeline

• Start date: 2017-12-04
• Primary completion: 2018-03-03
• Completion: 2018-06-30
• First posted: 2020-09-04
• Last updated: 2020-09-04

Locations

1 site across 1 country: Germany