Clinical Trials Directory

Trials / Terminated

TerminatedNCT04537832

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

ENVISION: Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies

Status
Terminated
Phase
Study type
Observational
Enrollment
58 (actual)
Sponsor
Encoded Therapeutics · Industry
Sex
All
Age
6 Months – 60 Months
Healthy volunteers
Not accepted

Summary

This is a multicenter, prospective, 2-year observational study in infants and children with developmental and epileptic encephalopathies (DEEs). The DEE currently being investigated is SCN1A-positive Dravet Syndrome.

Detailed description

This prospective, longitudinal, natural history master protocol has been designed to define the seizure, neurodevelopmental, and behavioral characteristics of SCN1A-positive Dravet Syndrome in infants and children between 6 and 60 months. It will also explore the impact of the disease on the participant's parent/caregiver quality of life (QoL) and healthcare resource utilization (HCRU).

Conditions

Interventions

TypeNameDescription
OTHERNo InterventionNo Intervention

Timeline

Start date
2021-01-18
Primary completion
2023-03-31
Completion
2023-03-31
First posted
2020-09-03
Last updated
2023-06-12

Locations

16 sites across 4 countries: United States, Australia, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT04537832. Inclusion in this directory is not an endorsement.