NCT04536324

The Absorption Rate of Subcutaneous Infused Fluid

The Absorption Rate of Subcutaneous Infused Fluid in Both Acutely Ill and Healthy Older Adults

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 6 (actual)
• Sponsor: Aalborg University Hospital · Academic / Other
• Sex: All
• Age: 75 Years – 120 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to examine the rate of absorption of subcutaneous infused fluid in older adults when acutely ill compared to when they are not acutely ill.

Detailed description

Dehydration is a common condition in older adults. When oral hydration is insufficient there is a need for parenteral hydration. Subcutaneous infused fluid or hypodermoclysis is a method for parenteral hydration. This method is used to treat older adults with mild to moderate dehydration or at risk of dehydration. Despite that, this method is used in older adults who are acutely ill we have a very limited understanding of the absorption time and thereby when the infused fluid is available in the circulatory system. This study aims to compare the absorption time in older adults who are acutely ill with when they are not acutely ill. Furthermore, this study aims to describe how fast the subcutaneous infused fluid is absorbed from the subcutaneous space and subsequently when it is available in the circulatory system where it has its effect.

Conditions

• Aged, 75 and Over
• Aged
• Hypodermoclysis
• Fluid Therapy
• Dehydration

Interventions

Type	Name	Description
PROCEDURE	Subcutaneous parenteral hydration	Patients will twice receive a subcutaneous infusion of 250 ml isotonic sodium chloride (NaCl) with 30 MBq Tc-99m pertechnetate mixed in. The patients will receive the first infusion during admission to our geriatric ward (when they are acutely ill) and the second infusion approximately 8 weeks after discharge when they are no longer acutely ill. The subcutaneous access will be placed on the abdomen in the lower left or right quadrant.

Timeline

• Start date: 2020-09-01
• Primary completion: 2020-11-20
• Completion: 2020-11-20
• First posted: 2020-09-02
• Last updated: 2021-02-04

Locations

1 site across 1 country: Denmark