Clinical Trials Directory

Trials / Terminated

TerminatedNCT04536077

Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients

Testing the Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Washington University School of Medicine · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The central hypothesis is that the addition of CDX-301 to CDX-1140 radically improves anti-tumor immunity in patients with pancreatic ductal adenocarcinoma.

Conditions

Interventions

TypeNameDescription
DRUGCDX-301The drug will be supplied free of charge by Celldex
DRUGCDX-1140The drug will be supplied free of charge by Celldex
PROCEDUREResearch blood drawAt screening; prior to first therapeutic dose of CDX-1140, on the day of the infusion; and at the time of surgery

Timeline

Start date
2021-08-13
Primary completion
2023-11-21
Completion
2023-11-21
First posted
2020-09-02
Last updated
2024-10-08
Results posted
2024-10-08

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04536077. Inclusion in this directory is not an endorsement.