Clinical Trials Directory

Trials / Completed

CompletedNCT04535986

A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

A Phase III Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ensifentrine Over 24 Weeks (With a 48-week Safety Subset) in Subjects With Moderate to Severe COPD

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
763 (actual)
Sponsor
Verona Pharma plc · Industry
Sex
All
Age
40 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of ensifentrine in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

Conditions

Interventions

TypeNameDescription
DRUGEnsifentrineDosage Formulation: Ensifentrine Nebulizer suspension Dosage 3mg Frequency: Twice Daily for 24 weeks or 48 weeks
DRUGPlaceboDosage Formulation: Ensifentrine Placebo Nebulizer solution Frequency: Twice Daily for 24 weeks or 48 weeks

Timeline

Start date
2020-09-29
Primary completion
2022-09-12
Completion
2022-12-02
First posted
2020-09-02
Last updated
2023-11-13
Results posted
2023-11-13

Locations

122 sites across 12 countries: United States, Bulgaria, Czechia, Germany, Greece, Hungary, Poland, Romania, Russia, Slovakia, South Korea, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04535986. Inclusion in this directory is not an endorsement.