NCT04535219

Effect of Total Sleep Deprivation on Vascular Function

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Insufficient sleep is associated with an increased risk for cardiovascular disease. The causal mechanisms are currently unknown, but may include endothelial dysfunction. The purpose of this study is to examine the influence of sex and aging on the effects of total sleep deprivation on vascular function and whether exercise training attenuates these effects.

Conditions

• Sleep Deprivation

Interventions

Type	Name	Description
OTHER	Exercise	60 minutes of moderate-intensity treadmill exercise (70% of maximal heart rate determined from the maximal graded exercise test)
OTHER	Supervised Total Sleep Deprivation	Laboratory-monitored total sleep deprivation

Timeline

• Start date: 2021-07-11
• Primary completion: 2022-08-02
• Completion: 2022-08-02
• First posted: 2020-09-01
• Last updated: 2023-08-29

Locations

1 site across 1 country: United States