NCT04527770

Midazolam Versus Dexamethasone as an Adjuvant to Local Anesthetics in the Ultrasound Guided Hydrodissection of Median Nerve for Treatment of Carpal Tunnel Syndrome Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 134 (actual)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

midazolam and dexamethasone both can counteract chronic pain. either via GABA mimetic action or via anti prostaglandins

Detailed description

Entrapement syndrome - namely median nerve compression in carpal tunnel syndrome - causes chronic pain that can be refractory to medical treatment . Ultrasound guided hydrodissection is an option for alleviating pain . Recurrence is the main side effect of injection. We try in this research to prevent recurrence rate . Midazolam and dexamethasone both are used in chronic pain . Midazolm act by GABA mimetic action while dexamethasone act by decrease interleukin formation

Conditions

• Pain Syndrome

Interventions

Type	Name	Description
DRUG	Dexamethasone	Ultrasound guided median nerve hydrodiseection using dexamethasone or midazolam
DRUG	Midazolam injection	intracarpal injection of midazolam and bupivacaine 0.5%

Timeline

• Start date: 2020-09-01
• Primary completion: 2021-03-01
• Completion: 2021-04-30
• First posted: 2020-08-27
• Last updated: 2022-02-18

Locations

1 site across 1 country: Egypt