NCT04527172

Neuromuscular Ultrasonography Utility for Detection of Peripheral Neuropathy in Systemic Lupus Erythematosus

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 55 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate the rule of NMUS in detection of peripheral neuropathy in SLE patient and to correlate it to traditional neurophysiological studies, clinical signs and activity of SLE.

Detailed description

The frequency of SLE peripheral neuropathy documented by electrophysiology has been estimated to be approximately 30%. The term peripheral neuropathies include symmetric polyneuropathy, single and multiple mononeuropathy, and radiculopathy. There has been increasing interest in using ultrasonography (US) to aid peripheral neuropathy diagnosis and studies have shown good correlation with other imaging modalities. US is a non-invasive and inexpensive imaging device that has become widely available as a diagnostic tool at many fields. so systemic lupus patients were enrolled in the study , performed nerve conduction study and neuromuscular ultrasound for bil. median, ulnar, peroneal, tibial and sural nerves , on statistics the cross sections were compared in neurophusiologically affected and non affected nerves, also the sensitivity and specifity of NMUS in comparison to the traditional NCS was calculated

Conditions

• Peripheral Neuropathy
• System; Lupus Erythematosus

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	neuromuscular ultrasound	ultrasound to visualize the peripheral nerves of lupus patients and to compare it with results of the raditional electrophysiological studies

Timeline

• Start date: 2018-05-20
• Primary completion: 2019-05-28
• Completion: 2020-05-15
• First posted: 2020-08-26
• Last updated: 2020-08-28

Locations

1 site across 1 country: Egypt