NCT04522154

Transcatheter Tricuspid Valve Interventions and Right Ventricular Function: Evaluation with Magnetic Resonance Imaging

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Heart and Diabetes Center North-Rhine Westfalia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

There is an urgent need for transcatheter tricuspid interventions, as pharmaceutical therapy becomes ineffective in advanced disease stages and surgery remains associated with high mortality rates. Despite the promising results, in some patients, although good procedural results were achieved, no clinical improvements were measured. Right ventricular dysfunction is suspected to be the cause of the failed therapeutic strategy. Therefore this study aims to analyze right ventricular function with magnet resonance imaging before and 3-months after the procedure in order to gain insight into the prevalence and dynamics of right ventricular dysfunction in severe tricuspid regurgitation and to identify possible predictors for treatment failure.

Conditions

• Tricuspid Valve Insufficiency

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Magnet resonance imaging	Patients will receive a cardiac magnet resonance tomography before and 3-month after the procedure

Timeline

• Start date: 2020-08-01
• Primary completion: 2025-03-09
• Completion: 2025-03-09
• First posted: 2020-08-21
• Last updated: 2025-03-12

Locations

1 site across 1 country: Germany